Dr. med.
Anna-Theresa Lipp

More than just a job: my passion for medicine

I am more than familiar with the human side of this disease - because I myself was diagnosed with lipoedema. Several years and operations have passed since then. In the meantime, I have arrived healthy (and relieved) in my "life 2.0".

That's exactly what my work is all about: the combination of professional expertise and personal experience (and a surname that also happens to fit quite well).

I discovered my calling in my work. I was struggling with lipoedema myself and couldn't find any answers because the literature and science on this condition was still very scarce. Today, I am glad that I have not only won the battle against lipoedema myself, but that I am also able to accompany many patients every day into a new, happy life free of complaints. My greatest joy are satisfied, happy patients and their excellent feedback.

As a doctor and specialist in lipoedema, I know how to give my patients a new zest for life and a feeling of freedom. My professional expertise from my time at the Rechts der Isar University Hospital (MRI) in Munich as well as numerous lipoedema research projects, expert activities, further training, specialist publications and lectures help me to do this.

An excerpt from my scientific work

Cell biology study

"Cell biology and protein expression studies on adipocytes from lipedema patients compared to healthy patients", Journal of Plastic and Reconstructive Surgery 2019

Objective of the cell biology study

The cause of lipoedema is still unknown. A genetic component is assumed on the basis of positive family histories, as well as a hormonal component due to the almost exclusively female patients and an outbreak of the disease or its progression in the phases of hormonal changes. In addition, a certain "vascular fragility" is noticeable in lipoedema patients, which can lead to hematomas on the extremities even with minor trauma. Due to the lack of scientific data on the pathogenesis of lipoedema, the aim of this study was to shed light on the molecular aetiopathogenesis of this clinical picture.

Epidemiological study

"New findings on lipedema - a retrospective postoperative data analysis of 209 patients with lipedema", Plastic and Reconstructive Surgery 2019

Objective of the epidemiological study

Lipedema is characterized by localized adipose tissue proliferation and edema of the extremities that typically does not respond to dietary regimens or physical activity. Although the disease is well described and affects a large number of women worldwide, little is known about its etiopathogenesis.

Research

• Ernst AM, Bauer H, Bauer HC, Steiner M, Malfertheiner A, Lipp AT. Lipedema Research-Quo Vadis? J Pers Med. 2022 Dec 31;13(1):98. doi: 10.3390/jpm13010098. PMID: 36675759; PMCID: PMC9860653.
• Ernst AM, Steiner M, Kainz V, Tempfer H, Spitzer G, Plank T, Bauer HC, Bresgen N, Habenbacher A, Bauer H, Lipp AT. "Lipedema: The use of cultured adipocytes for identification of diagnostic markers". Plast Reconstr Surg. 2023 Mar 14. doi: 10.1097/PRS.0000000000010392. Epub ahead of print. PMID: 36912938.
• Bauer AT, von Lukowicz D, Lossagk K, Aitzetmueller M, Moog P, Cerny M, Erne H, Schmauss D, Duscher D, Machens HG. New Insights on Lipedema: The Enigmatic Disease of the Peripheral Fat. Plast Reconstr Surg. 2019 Dec;144(6):1475-1484. doi: 10.1097/PRS.0000000000006280. PMID: 31764671.
• Bauer AT, von Lukowicz D, Lossagk K, Hopfner U, Kirsch M, Moog P, Bauer H, Machens HG, Schmauss D. Adipose Stem Cells from Lipedema and Control Adipose Tissue Respond Differently to Adipogenic Stimulation In Vitro. Plast Reconstr Surg. 2019 Sep;144(3):623-632. doi: 10.1097/PRS.0000000000005918. PMID: 31461015.
• Hadjipanayi E, Bauer AT, Moog P, Salgin B, Kuekrek H, Fersch B, Hopfner U, Meissner T, Schlüter A, Ninkovic M, Machens HG, Schilling AF. Cell-free carrier system for localized delivery of peripheral blood cell-derived engineered factor signaling: towards development of a one-step device for autologous angiogenic therapy. J Control Release. 2013 Jul 10;169(1-2):91-102. doi: 10.1016/j.jconrel.2013.04.008. Epub 2013 Apr 19. PMID: 23603614.
• Hadjipanayi E, Moog P, Bekeran S, Kirchhoff K, Berezhnoi A, Aguirre J, Bauer AT, Kükrek H, Schmauss D, Hopfner U, Isenburg S, Ntziachristos V, Ninkovic M, Machens HG, Schilling AF, Dornseifer U. In Vitro Characterization of Hypoxia Preconditioned Serum (HPS)-Fibrin Hydrogels: Basis for an Injectable Biomimetic Tissue Regeneration Therapy. J Funct Biomater. 2019 May 13;10(2):22. doi: 10.3390/jfb10020022. PMID: 31086048; PMCID: PMC6616457.
• Moog P, Tinwald I, Aitzetmueller M, Bauer AT, Megerle K, Machens HG, Laszlo Kovacs L, Kuekrek H. The Usage of Pedicled or Free Muscle Flaps Represents a Beneficial Approach for Periprosthetic Infection After Knee Arthroplasty. Ann Plast Surg. 2020 Nov;85(5):539-545. doi: 10.1097/SAP.0000000000002293. PMID: 32079811.
• Hadjipanayi E, Cheema U, Hopfner U, Bauer A, Machens HG, Schilling AF. Injectable system for spatio-temporally controlled delivery of hypoxia-induced angiogenic signaling. J Control Release. 2012 Aug 10;161(3):852-60. doi: 10.1016/j.jconrel.2012.04.048. Epub 2012 May 22. PMID: 22634070.
• Moog P, Jensch M, Betzl J, Bauer AT, Cerny MK, Schmauss D, Kükrek H, Erne H, Machens HG, Megerle K. Bacterial bioburden of wounds: influence of debridement and negative-pressure wound therapy (NPWT). J Wound Care. 2021 Aug 2;30(8):604-611. doi: 10.12968/jowc.2021.30.8.604. PMID: 34382852.
• Cerny MK, Moog P, Bauer AT, Schmauss D, Varga L, Aitzetmueller MM, Machens HG, Duscher D, Erne H. Lipofilling of Fingertips for Volume Defects after Fingertip Injuries. Ann Plast Surg. 2018 Dec;81(6):653-656. doi: 10.1097/SAP.0000000000001587. PMID: 30067529.
• Cerny M, Hellmich S, Schwarz-Boeger U, Schmauss D, Moog P, Bauer AT, Pförringer D, Erne H, Machens HG, Megerle K. DRG Erlöse und Kosten multimorbider Patienten im deutschen DRG-System - Analyse der operativer Behandlung chronischer Wunden an einer Universitätsklinik am Beispiel des Dekubitus [DRG revenues and costs of multimorbid patients in the German DRG system - Analysis of the surgical treatment of chronic wounds at a university hospital based on the example of pressure ulcers]. Handchir Mikrochir Plast Chir. 2018 Aug;50(4):284-290. German. doi: 10.1055/a-0621-9324. Epub 2018 Aug 21. PMID: 30130832.
• Moog P, Kirchhoff K, Bekeran S, Bauer AT, von Isenburg S, Dornseifer U, Machens HG, Schilling AF, Hadjipanayi E. Comparative Evaluation of the Angiogenic Potential of Hypoxia Preconditioned Blood-Derived Secretomes and Platelet-Rich Plasma: An In Vitro Analysis. Biomedicines. 2020 Jan 16;8(1):16. doi: 10.3390/biomedicines8010016. PMID: 31963131; PMCID: PMC7168246.
• Hadjipanayi E, Kuhn PH, Moog P, Bauer AT, Kuekrek H, Mirzoyan L, Hummel A, Kirchhoff K, Salgin B, Isenburg S, Dornseifer U, Ninkovic M, Machens HG, Schilling AF. The Fibrin Matrix Regulates Angiogenic Responses within the Hemostatic Microenvironment through Biochemical Control. PLoS One. 2015 Aug 28;10(8):e0135618. doi: 10.1371/journal.pone.0135618. PMID: 26317771; PMCID: PMC4552838.
• Kwak MS, Bauer AT, Machens HG. Immediate finger soft tissue reconstruction with a free neurovascular dorsoradial artery perforator flap (DRAP): reliable supermicrosurgery? [Immediate finger soft tissue reconstruction with a free neurovascular dorsoradial artery perforator flap (DRAP): reliable supermicrosurgery?] Handchir Mikrochir Plast Chir. 2019 Jun;51(3):205-206. German. doi: 10.1055/a-0900-4104. Epub 2019 Jun 5. PMID: 31167281.
• Erne HC, Cerny MK, Ehrl D, Bauer AT, Schmauss V, Moog P, Broer PN, Loew S, Schmauss D. Autologous Fat Injection versus Lundborg Resection Arthroplasty for the Treatment of Trapeziometacarpal Joint Osteoarthritis. Plast Reconstr Surg. 2018 Jan;141(1):119-124. doi: 10.1097/PRS.0000000000003913. PMID: 28922320.